BDBM50375592 CHEMBL412272

SMILES C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI Key InChIKey=AWDRATDZQPNJFN-VAYUFCLWSA-N

Data  1 KI  1 IC50  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375592   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University

Curated by ChEMBL
LigandPNGBDBM50375592(CHEMBL412272)
Affinity DataEC50:  680nMAssay Description:Agonist activity at wild type human TGR5 expressed in HEK293 cells assessed as rise in intracellular cAMP level incubated for 16 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University

Curated by ChEMBL
LigandPNGBDBM50375592(CHEMBL412272)
Affinity DataEC50:  8.90E+3nMAssay Description:Agonist activity at human TGR5 Y89A mutant expressed in HEK293 cells assessed as rise in intracellular cAMP level incubated for 16 hrs by luciferase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Heinrich Heine University

Curated by ChEMBL
LigandPNGBDBM50375592(CHEMBL412272)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed