BDBM50376788 CHEMBL257997

SMILES CC(C)Cc1cn(-c2nc(cs2)C([O-])=O)c2cc(Cl)ccc12

InChI Key InChIKey=FECWOVCONGPURJ-UHFFFAOYSA-M

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376788   

TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50376788(CHEMBL257997)
Affinity DataKi:  0.5nMAssay Description:Antagonist activity against human EP1 receptor expressed in CHOK1 cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50376788(CHEMBL257997)
Affinity DataIC50:  6.30nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed