BDBM50377302 CHEMBL255930
SMILES Cc1oc(nc1CCOc1ccc(C[C@@H]2CN(C[C@@H]2C(O)=O)c2nccc(n2)C(F)(F)F)cc1)-c1ccccc1
InChI Key InChIKey=ABIFPJDABNXEMK-GGAORHGYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50377302
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at GAL4 tagged human PPARalpha ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Agonist activity at GAL4 tagged human PPARgamma ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Agonist activity at GAL4 tagged human PPARgamma ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataEC50: 1.65E+5nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as luciferase activity by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity to PPARgamma (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization bindi...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at GAL4 tagged human PPARalpha ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Binding affinity to PPARalpha (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization bindi...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Binding affinity to PPARalpha (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization bindi...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataEC50: 7.00E+3nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells assessed as luciferase activity by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Bristol-Myers Squibb Research And Development (R & D)
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity to PPARgamma (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization bindi...More data for this Ligand-Target Pair