BDBM50383274 CHEMBL1229592::US10167264, WZ4002::US9670213, WZ4002
SMILES COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(C)CC1
InChI Key InChIKey=ITTRLTNMFYIYPA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50383274
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of wild type recombinant human EGFR preincubated for 10 mins followed by FAM-labeled peptide/ATP addition measured after 1 hr by mobility ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant EGFR T790M/L858R double mutant preincubated for 10 mins followed by FAM-labeled peptide/ATP addition measured after 1...More data for this Ligand-Target Pair