BDBM50392001 CHEMBL2152305

SMILES C(N1CCC(CC1)n1cnc2cnc3[nH]ccc3c12)c1ccccc1

InChI Key InChIKey=WKWXJWGOAKGEEM-UHFFFAOYSA-N

Data  4 KI  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50392001   

TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50392001(CHEMBL2152305)
Affinity DataKi:  2.40nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50392001(CHEMBL2152305)
Affinity DataKi:  4.40nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50392001(CHEMBL2152305)
Affinity DataKi:  33nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50392001(CHEMBL2152305)
Affinity DataKi:  85nMAssay Description:Inhibition of TYK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50392001(CHEMBL2152305)
Affinity DataEC50:  86nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL2-induced STAT3 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed