BDBM50393642 CHEMBL2158685
SMILES Clc1ccc(cc1)C12CC3CC(CC(C3)(C1)C(=O)NCc1ccncc1)C2
InChI Key InChIKey=CAOTVXGYTWCKQE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50393642
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of human recombinant SphK2 using NBD-sphingosine as substrate after 2 hrs by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Binding affinity to recombinant SphK2 (unknown origin) ADP Quest assay systemMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Competitive inhibition of human recombinant SphK2 assessed as NBD-S1P formation using NBD-Sph as substrate by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Binding affinity to Sphk2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged full length SphK2 expressed in baculovirus infected Sf9 cells using C17-sphingosine as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged Sphk2 (2 to 593 residues) expressed in Escherichia coli using varying level of sphingosine as s...More data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged SK2 expressed in baculovirus infected Sf9 insect cells using NBD-Sph as substrate m...More data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of SPHK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of recombinant human SPHK2 using sphingosine as substrate by ADP-Quest assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair