BDBM50394616 CHEMBL2164577

SMILES Cn1cc(cn1)-c1cccc2Nc3nc(ccc3CN(c12)S(=O)(=O)c1ccc(cc1)C(C)(C)C)C(F)(F)F

InChI Key InChIKey=RHQUWOJHFDJROP-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394616   

TargetBombesin receptor subtype-3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50394616(CHEMBL2164577)
Affinity DataEC50:  102nMAssay Description:Agonist activity at mouse BRS-3 expressed in HEK293AEQ cells assessed as bioluminescence for 10 mins by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50394616(CHEMBL2164577)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as bioluminescence for 10 mins by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50394616(CHEMBL2164577)
Affinity DataIC50: 0.760nMAssay Description:Displacement of [125I]-dY-peptide from human BRS-3 expressed in NFAT-CHO cells after 2 hrs by by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50394616(CHEMBL2164577)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed