BDBM50394618 CHEMBL2164575

SMILES Cc1ccc2Nc3nc(ccc3CN(c2c1C)S(=O)(=O)c1ccc(cc1)C(C)(C)C)C(F)(F)F

InChI Key InChIKey=OAIVSBLLDFJYMS-UHFFFAOYSA-N

Data  3 IC50  11 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50394618   

TargetBombesin receptor subtype-3(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  97nMAssay Description:Agonist activity at human BRS3 expressed in CHO-K1 cells by IP-One HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  33nMAssay Description:Agonist activity at mouse BRS3 expressed in CHO-K1 cells by IP-One HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  677nMAssay Description:Activation of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  33nMAssay Description:Agonist activity at mouse BRS-3 expressed in CHOK1 cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  97nMAssay Description:Agonist activity at human BRS-3 expressed in CHOK1 cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  678nMAssay Description:Activation of human PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mouse BRS3 expressed in HEK293 cells expressing aequorin measured for 30 secs by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  33nMAssay Description:Agonist activity at mouse BRS3 expressed in HEK293 cells expressing aequorin measured for 30 secs by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human BRS3 expressed in HEK293 cells expressing aequorin measured for 10 mins by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human BRS3 expressed in HEK293 cells expressing aequorin measured for 30 secs by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataEC50:  97nMAssay Description:Agonist activity at human BRS3 expressed in HEK293 cells expressing aequorin measured for 30 secs by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataIC50: 169nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin(6-14) from human BRS3 expressed in CHO cells expressing NFAT after 2 hrs by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50394618(CHEMBL2164575)
Affinity DataIC50: 169nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin(6-14) from human BRS3 expressed in CHO cells expressing NFAT after 2 hrs by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed