BDBM50394681 CHEMBL2165620

SMILES OC(=O)c1ccc(NC(=O)[C@H](CC2CCCC2)n2cnc(c2)C(F)(F)F)nc1

InChI Key InChIKey=GKMLFBRLRVQVJO-ZDUSSCGKSA-N

Data  3 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394681   

TargetHexokinase-4(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50394681(CHEMBL2165620)
Affinity DataEC50:  6.90E+3nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as stimulation of glucose-induced insulin secretionMore data for this Ligand-Target Pair
TargetHexokinase-4(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50394681(CHEMBL2165620)
Affinity DataEC50:  190nMAssay Description:Induction of glucokinase translocation from nucleus to cytoplasm in cryopreserved rat hepatocytes after 1 hr by Hoechst staining-based fluorescence m...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50394681(CHEMBL2165620)
Affinity DataEC50:  90nMAssay Description:Activation of human recombinant glucokinase using 6.5 mM glucose by spectrophotometric analysisMore data for this Ligand-Target Pair