BDBM50396967 CHEMBL2170806

SMILES N[C@@H]1CCN(C1)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1

InChI Key InChIKey=MPTVBCUATPSHDI-CQSZACIVSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396967   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50396967(CHEMBL2170806)
Affinity DataKi:  7nMAssay Description:Competitive inhibition of N-terminal His6-tagged recombinant human c-MET (974 to 1390 amino acids) by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50396967(CHEMBL2170806)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at c-MET receptor in human A549 cells assessed as inhibition of autophosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed