BDBM50397558 CARPROFEN::CHEMBL2171249

SMILES C[C@H](C(O)=O)c1ccc2c(c1)[nH]c1ccc(Cl)cc21

InChI Key InChIKey=PUXBGTOOZJQSKH-QMMMGPOBSA-N

Data  3 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50397558   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50397558(CARPROFEN | CHEMBL2171249)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human COX2 pre-incubated for 10 mins before substrate addition by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50397558(CARPROFEN | CHEMBL2171249)
Affinity DataIC50:  6.42E+4nMAssay Description:Inhibition of FAAH in rat brain homogenates pre-incubated for 10 mins before addition of [3H]anandamide and [3H]AEA substrates for 30 mins by liquid ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50397558(CARPROFEN | CHEMBL2171249)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of ovine COX1 pre-incubated for 10 mins before arachidonic acid substrate addition by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed