BDBM50399207 CHEMBL2180179

SMILES Brc1cccc(c1)C1=NCC(=O)Nc2c1oc1ccccc21

InChI Key InChIKey=NKYMVQPXXTZHSF-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50399207   

TargetP2X purinoceptor 4(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50399207(CHEMBL2180179)
Affinity DataIC50:  9.20E+3nMAssay Description:Antagonist activity at human P2X4R transfected in HEK293 cells assessed as inhibition of ATP-mediated calcium influx measured after 10 mins by YOPRO-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50399207(CHEMBL2180179)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at human P2X4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50399207(CHEMBL2180179)
Affinity DataIC50:  9.20E+3nMAssay Description:Antagonist activity at human P2X4R transfected in HEK293 cells assessed as inhibition of ATP-mediated calcium influx measured after 10 mins by YOPRO-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50399207(CHEMBL2180179)
Affinity DataIC50:  5.70E+3nMAssay Description:Antagonist activity at human P2X4R transfected in 1321N1 cells assessed as inhibition of ATP-mediated calcium influx measured after 10 mins by Fura-2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50399207(CHEMBL2180179)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at human P2X4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 4(Human)
University of East Anglia

Curated by ChEMBL
LigandPNGBDBM50399207(CHEMBL2180179)
Affinity DataIC50:  5.70E+3nMAssay Description:Antagonist activity at human P2X4R transfected in 1321N1 cells assessed as inhibition of ATP-mediated calcium influx measured after 10 mins by Fura-2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed