BDBM50400564 CHEMBL2206242

SMILES CCCn1cnc2c(NCc3ccc(C)s3)nc(N[C@H](CC)CO)nc12

InChI Key InChIKey=DPTXJOUVBMUSGY-CYBMUJFWSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50400564   

LigandPNGBDBM50400564(CHEMBL2206242)
Affinity DataEC50:  2.06E+4nMAssay Description:Inhibition of human Cdk1/cyclin B activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50400564(CHEMBL2206242)
Affinity DataEC50:  8.80E+3nMAssay Description:Agonist activity at P/Q-type Cav2.1 expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400564(CHEMBL2206242)
Affinity DataEC50:  7.21E+3nMAssay Description:Agonist activity at N-type Cav2.2 channel expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400564(CHEMBL2206242)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of human MAPK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400564(CHEMBL2206242)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at L-type Cav1.3 expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400564(CHEMBL2206242)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of human MLCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400564(CHEMBL2206242)
Affinity DataEC50:  3.03E+3nMAssay Description:Inhibition of human Cdk5/p35 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed