BDBM50400815 (S)-VENLAFAXINE::VENLAFAXINE

SMILES COc1ccc(cc1)[C@@H](CN(C)C)C1(O)CCCCC1

InChI Key InChIKey=PNVNVHUZROJLTJ-MRXNPFEDSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400815   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50400815((S)-VENLAFAXINE | VENLAFAXINE)
Affinity DataIC50:  149nMAssay Description:Inhibition of NET (unknown origin) assessed as noradrenaline reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50400815((S)-VENLAFAXINE | VENLAFAXINE)
Affinity DataIC50:  754nMAssay Description:Inhibition of human NET expressed in MDCK cells assessed as decrease in [3H]-noradrenaline reuptake after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50400815((S)-VENLAFAXINE | VENLAFAXINE)
Affinity DataIC50:  754nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed