BDBM50400870 CHEMBL559569::SB-612111

SMILES Cc1cccc2C(O)CC(CN3CCC(CC3)c3c(Cl)cccc3Cl)CCc12

InChI Key InChIKey=OHRDCQFCAWLDBP-UHFFFAOYSA-N

Data  7 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50400870   

TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50400870(CHEMBL559569 | SB-612111)
Affinity DataKi:  0.253nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50400870(CHEMBL559569 | SB-612111)
Affinity DataKi:  0.253nMAssay Description:Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by microbeta scintillation countingMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50400870(CHEMBL559569 | SB-612111)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]nociceptin from recombinant human nociceptin opioid receptor expressed in CHO cell membranes after 60 mins by scintillation count...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50400870(CHEMBL559569 | SB-612111)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu opioid receptor expressed in CHO cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50400870(CHEMBL559569 | SB-612111)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50400870(CHEMBL559569 | SB-612111)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50400870(CHEMBL559569 | SB-612111)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed