BDBM50408664 GR-205171::VOFOPITANT

SMILES COc1ccc(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)-n1nnnc1C(F)(F)F

InChI Key InChIKey=XILNRORTJVDYRH-HKUYNNGSSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50408664   

TargetSubstance-P receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408664(GR-205171 | VOFOPITANT)
Affinity DataKi:  0.0251nMAssay Description:Inhibition of [3H]-substance P binding to human NK1 receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetSubstance-P receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408664(GR-205171 | VOFOPITANT)
Affinity DataKi:  0.0501nMAssay Description:Displacement of [3H]substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50408664(GR-205171 | VOFOPITANT)
Affinity DataIC50:  0.0800nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed