BDBM504171 N-[2,2-dimethyl-6-[4-[(4- methyl-1H-imidazol-5- yl)methyl]piperazin-1-yl]-3H- benzofuran-5-yl]pyrazolo[l,5- a]pyrimidine-3-carboxamide::US11034698, Example 8

SMILES Cc1nc[nH]c1CN1CCN(CC1)c1cc2OC(C)(C)Cc2cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=IVPMLNHDTNCDFC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504171   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504171(N-[2,2-dimethyl-6-[4-[(4- methyl-1H-imidazol-5- yl...)
Affinity DataKi:  3.80nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent