BDBM50418334 CHEMBL1770298

SMILES Cc1ccc(s1)C(NC(=O)c1ccccc1O)C(=O)Nc1c(C)cccc1C

InChI Key InChIKey=AHTURLVFIJHCLS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50418334   

TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418334(CHEMBL1770298)
Affinity DataIC50:  398nMAssay Description:Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418334(CHEMBL1770298)
Affinity DataIC50:  1.58E+3nMAssay Description:Antagonist activity at human FPR1 in expressed in HEK293 cells assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation after 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50418334(CHEMBL1770298)
Affinity DataIC50:  2.51E+4nMAssay Description:Antagonist activity at mouse FPR1 expressed in HEK293 cells assessed as inhibition of fMLFF-stimulated intracellular calcium mobilisation by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed