BDBM504201 (R)-5-(3-Aminopiperidin-1-yl)- N-(6-methoxy-2,2-dimethyl-2,3- dihydrobenzofuran-5- yl)pyrazolo[1,5-a]pyrimidine-3- carboxamide::US11034698, Example 39

SMILES COc1cc2OC(C)(C)Cc2cc1NC(=O)c1cnn2ccc(nc12)N1CCC[C@@H](N)C1

InChI Key InChIKey=IYTJTQQPGWLCAU-OAHLLOKOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504201   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504201((R)-5-(3-Aminopiperidin-1-yl)- N-(6-methoxy-2,2-di...)
Affinity DataKi:  4.10nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent