BDBM50423877 DIHYDROTANSHINONE::Dihydrotanshinone I::acs.jmedchem.1c00409_ST.562

SMILES C[C@H]1COC2=C1C(=O)C(=O)c1c2ccc2c(C)cccc12

InChI Key InChIKey=HARGZZNYNSYSGJ-UHFFFAOYSA-N

Data  10 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50423877   

TargetELAV-like protein 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50423877(Dihydrotanshinone I | DIHYDROTANSHINONE | acs.jmed...)
Affinity DataIC50: 149nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE TNFalpha complex formation after 3 hrs by REMSA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetELAV-like protein 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50423877(Dihydrotanshinone I | DIHYDROTANSHINONE | acs.jmed...)
Affinity DataIC50: 68nMAssay Description:Inhibition of ELAV1 (unknown origin)-ARE TNFalpha complex formation after 90 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetELAV-like protein 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50423877(Dihydrotanshinone I | DIHYDROTANSHINONE | acs.jmed...)
Affinity DataKi:  50nMAssay Description:Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed