BDBM504245 N-[6-Morpholino-2-(2- oxaspiro[3,3]heptan-6-yl)-1- oxo-isoindolin-5- yl]pyrazolo[1,5-a]pyrimidine-3- carboxamide::US11034698, Example 94

SMILES O=C(Nc1cc2CN(C3CC4(COC4)C3)C(=O)c2cc1N1CCOCC1)c1cnn2cccnc12

InChI Key InChIKey=GRDHJEQESXHROS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504245   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504245(N-[6-Morpholino-2-(2- oxaspiro[3,3]heptan-6-yl)-1-...)
Affinity DataKi:  4.90nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent