BDBM50426963 CHEMBL2325084

SMILES Cc1cc2oc(nc2cc1Cl)N1CCC(CC1)C(=O)N[C@H]1CCC[C@H](CO)C1

InChI Key InChIKey=BVUIHNKCEFPMBL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426963   

TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426963(CHEMBL2325084)
Affinity DataIC50: 338nMAssay Description:Inhibition of mPGES-1-mediated PGE2 production in LPS-stimulated healthy human whole blood after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426963(CHEMBL2325084)
Affinity DataIC50: 25nMAssay Description:Inhibition of mPGES-1 (unknown origin) using PGH2 as substrate assessed as PGE2 synthesis by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426963(CHEMBL2325084)
Affinity DataIC50: 340nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426963(CHEMBL2325084)
Affinity DataIC50: 25nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed