BDBM50434129 CHEMBL2381647

SMILES N[C@H]1C[C@](N)([C@H]2[C@@H]1[C@@H]2C(O)=O)C(O)=O

InChI Key InChIKey=BIHSLTSGYFDSHV-UHFFFAOYSA-N

Data  2 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50434129   

TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human mGlu2 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human mGlu3 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)
Affinity DataKi:  284nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)
Affinity DataKi:  4.41E+3nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2019
Entry Details Article
PubMed