BDBM50435516 CHEMBL2392490

SMILES C(N1CCC(CC1)n1nnc2cnc3[nH]ccc3c12)c1cccnc1

InChI Key InChIKey=LCRYPUUOTORNEW-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50435516   

TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435516(CHEMBL2392490)
Affinity DataEC50:  414nMAssay Description:Inhibition of JAK1-mediated STAT3 phosphorylation in IL6-induced human TF1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435516(CHEMBL2392490)
Affinity DataKi:  16nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50435516(CHEMBL2392490)
Affinity DataKi:  28nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed