BDBM50438817 CHEMBL2413372

SMILES CN(Cc1ccc(F)cc1)C(=O)Cc1nc(c2ccccn12)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=AIXNJBWVNGPEMF-UHFFFAOYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438817   

TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica NV

Curated by ChEMBL
LigandPNGBDBM50438817(CHEMBL2413372)
Show SMILES CN(Cc1ccc(F)cc1)C(=O)Cc1nc(c2ccccn12)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C24H22FN3O3S/c1-27(16-18-10-12-20(25)13-11-18)23(29)15-22-26-24(21-9-5-6-14-28(21)22)32(30,31)17-19-7-3-2-4-8-19/h2-14H,15-17H2,1H3
Affinity DataIC50: 194nMAssay Description:Antagonist activity at human orexin receptor 2 expressed in CHO cells assessed as inhibition of orexin-A-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair