BDBM504402 US11040984, Compound 2

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1N1CC2(CCN(C)CC2)OC1=O

InChI Key InChIKey=PQHBTLFVLADREW-UHFFFAOYSA-N

Data  2 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504402   

TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
MEDSHINE DISCOVERY INC.

US Patent
LigandPNGBDBM504402(US11040984, Compound 2)
Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1N1CC2(CCN(C)CC2)OC1=O
Show InChI InChI=1S/C23H23ClFN5O3/c1-29-7-5-23(6-8-29)12-30(22(31)33-23)19-10-15-18(11-20(19)32-2)26-13-27-21(15)28-14-3-4-17(25)16(24)9-14/h3-4,9-11,13H,5-8,12H2,1-2H3,(H,26,27,28)
Affinity DataIC50: 48.1nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetEpidermal growth factor receptor [1-745,751-1210](Homo sapiens (Human))
MEDSHINE DISCOVERY INC.

US Patent
LigandPNGBDBM504402(US11040984, Compound 2)
Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1N1CC2(CCN(C)CC2)OC1=O
Show InChI InChI=1S/C23H23ClFN5O3/c1-29-7-5-23(6-8-29)12-30(22(31)33-23)19-10-15-18(11-20(19)32-2)26-13-27-21(15)28-14-3-4-17(25)16(24)9-14/h3-4,9-11,13H,5-8,12H2,1-2H3,(H,26,27,28)
Affinity DataIC50: 16.5nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid