BDBM50440284 CHEMBL2424780::US10457681, Compound Vesatolimod::US10487084, Compound Vesatolimod::US10508115, Compound Vesatolimod::US10654856, GS-9620::US10919895, Vesatolimod::US10981914, Compound Vesatolimod::US11242345, Example GS-9620::US9708325, GS-9620
SMILES CCCCOc1nc(N)c2NC(=O)CN(Cc3cccc(CN4CCCC4)c3)c2n1
InChI Key InChIKey=VFOKSTCIRGDTBR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50440284
Affinity DataEC50: 9.00E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells by reporter based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Affinity DataEC50: 517nMAssay Description:The compounds were gradient diluted with DMSO in 3-fold using liquid work station POD starting at a concentration of 10 mmol/L and 10 points were dil...More data for this Ligand-Target Pair
Affinity DataEC50: 7.87E+3nMAssay Description:The compounds were gradient diluted with DMSO in 3-fold using liquid work station POD starting at a concentration of 10 mmol/L and 10 points were dil...More data for this Ligand-Target Pair
Affinity DataEC50: 9.00E+3nMAssay Description:Agonist activity at human TLR8 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
Affinity DataEC50: 1.16E+4nMAssay Description:A stable HEK-Blue-hTLR8 cell line was purchased from InvivoGen (Cat. #: HEK-Blue-htlr8, San Diego, Calif., USA). These cells were designed for studyi...More data for this Ligand-Target Pair
Affinity DataEC50: 291nMAssay Description:Agonist activity at human TLR7 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ...More data for this Ligand-Target Pair