BDBM50440284 CHEMBL2424780::US10457681, Compound Vesatolimod::US10487084, Compound Vesatolimod::US10508115, Compound Vesatolimod::US10654856, GS-9620::US10919895, Vesatolimod::US10981914, Compound Vesatolimod::US11242345, Example GS-9620::US9708325, GS-9620

SMILES CCCCOc1nc(N)c2NC(=O)CN(Cc3cccc(CN4CCCC4)c3)c2n1

InChI Key InChIKey=VFOKSTCIRGDTBR-UHFFFAOYSA-N

Data  13 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440284   

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  800nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  1.16E+4nMAssay Description:A stable HEK-Blue-hTLR8 cell line was purchased from InvivoGen (Cat. #: HEK-Blue-htlr8, San Diego, Calif., USA). These cells were designed for studyi...More data for this Ligand-Target Pair
In DepthDetails US Patent