BDBM50440737 CHEMBL2431120

SMILES COc1ccccc1N1CCN(CC1)c1nc(nc2cc(OC)c(OC)cc12)C1CC1

InChI Key InChIKey=SWEOAXMICIJCQC-UHFFFAOYSA-N

Data  4 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50440737   

TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at NTR1 (unknown origin) expressed in human U2OS cells coexpressing beta-arrestin by GFP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataEC50:  2.87E+3nMAssay Description:Allosteric modulation of human GFP-fused PK-tagged Gq-coupled NTR1 expressed in CHOK1 cells assessed as induction of NT (8 to 13) peptide-mediated be...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at NTSR1 (unknown origin) expressed in CHO cells assessed as potentiation of NT(8-13) peptide-induced change in intracellular Ca2+ l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataEC50: >8.00E+4nMAssay Description:Agonist activity at NTR1 (unknown origin) expressed in CHO cells assessed as stimulation of calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)
Affinity DataEC50:  3.41E+3nMAssay Description:Agonist activity at NTR1 (unknown origin) expressed in CHOK1 cells by beta-arrestin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed