BDBM504410 US11040984, Compound 12
SMILES CN1CCC2(CN(C(=O)O2)c2ccc3ncnc(Nc4cccc(Cl)c4F)c3c2)CC1
InChI Key InChIKey=PSYAFMNESHTJGR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 504410
TargetEpidermal growth factor receptor [1-745,751-1210](Homo sapiens (Human))
Medshine Discovery
US Patent
Medshine Discovery
US Patent
Affinity DataIC50: 0.0850nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0170nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair