BDBM504411 US11040984, Compound 13

SMILES COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1N1CC2(CN(C)C2)OC1=O

InChI Key InChIKey=DZHGHOYCGHZFFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504411   

TargetEpidermal growth factor receptor [1-745,751-1210](Homo sapiens (Human))
Medshine Discovery

US Patent
LigandPNGBDBM504411(US11040984, Compound 13)
Affinity DataIC50:  0.0520nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Medshine Discovery

US Patent
LigandPNGBDBM504411(US11040984, Compound 13)
Affinity DataIC50:  0.0160nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent