BDBM50441297 CHEMBL2431664::CHEMBL2431666

SMILES O[C@H](c1cccc(c1)-c1ccc(cc1)C(=O)P(O)(O)O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=UFGNNGASNTXMIR-LJQANCHMSA-N

Data  6 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50441297   

TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  8.80E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  1.64E+5nMAssay Description:Inhibition of human TC-PTP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of human CD45 using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibition of human LAR using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKd:  2.72E+4nMAssay Description:Binding affinity to 6His-tagged STEP phosphatase domain (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21 Gold (DE3) after 90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed