BDBM50442103 CHEMBL2441082

SMILES COc1cc2c(NC3CCN(CC3)C(C)C)nc(nc2cc1OCCCN1CCCC1)N1CCC(F)(F)CC1

InChI Key InChIKey=RNAMYOYQYRYFQY-UHFFFAOYSA-N

Data  1 KI  22 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50442103   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GLP (unknown origin) incorporation of tritium-labeled methyl group to biotinylated peptide substrates by Scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of G9a (unknown origin) incorporation of tritium-labeled methyl group to biotinylated peptide substrates by Scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed