BDBM50444333 CHEMBL3094369
SMILES OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F
InChI Key InChIKey=XCJCRDUPVLFMDD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50444333
Affinity DataEC50: 19nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 89nMAssay Description:Inverse agonist activity at GAL4-fused human RORc expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Agonist activity at PXR (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 390nMAssay Description:Agonist activity at LXRbeta (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 720nMAssay Description:Agonist activity at LXRalpha (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at FXR (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Agonist activity at RoRa (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Agonist activity at RoRb (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 89nMAssay Description:Agonist activity at RoRc (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Displacement of [3H2]-25-hydroxycholesterol from N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial express...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair
Affinity DataEC50: 194nMAssay Description:Agonist activity at GAL4-fused human PXR expressed in HEK293T cells assessed as activation of basal transcriptional activity after 20 hrs by dual-glo...More data for this Ligand-Target Pair
Affinity DataEC50: 385nMAssay Description:Agonist activity at GAL4-fused human LXRbeta expressed in HEK293T cells assessed as activation of basal transcriptional activity after 20 hrs by dual...More data for this Ligand-Target Pair
Affinity DataEC50: 719nMAssay Description:Agonist activity at GAL4-fused human LXRalpha expressed in HEK293T cells assessed as activation of basal transcriptional activity after 20 hrs by dua...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at GAL4-fused human FXR expressed in HEK293T cells assessed as activation of basal transcriptional activity after 20 hrs by dual-glo...More data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Inverse agonist activity at GAL4-fused human RORa expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Inverse agonist activity at GAL4-fused human RORb expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs b...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Binding affinity to RORgamma (unknown origin)More data for this Ligand-Target Pair