BDBM50444943 CHEMBL3099773

SMILES COc1cccc(OC)c1-c1nc(cn1-c1ccnc2cc(Cl)ccc12)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key InChIKey=OUZUXYQXCXYGMX-IBGZPJMESA-N

Data  2 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50444943   

TargetSodium-dependent dopamine transporter(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of NTS1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 2(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)
Affinity DataEC50: >8.00E+4nMAssay Description:Agonist activity at NTR2 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at NTR1 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)
Affinity DataEC50: >4.00E+4nMAssay Description:Agonist activity at GPR35 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)
Affinity DataEC50:  298nMAssay Description:Agonist activity at NTSR1 (unknown origin) expressed in CHO cells assessed as potentiation of NT(8-13) peptide-induced change in intracellular Ca2+ l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)
Affinity DataEC50:  298nMAssay Description:Agonist activity at NTR1 (unknown origin) expressed in CHO cells assessed as Ca2+ mobilization by Fluo-4 NW dye-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)
Affinity DataEC50:  6.10E+3nMAssay Description:Agonist activity at NTR1 (unknown origin) expressed in CHO-K1 cells coexpressing beta-arrestin/N-terminal deletion mutant of beta-galactosidase fusio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed