BDBM50450447 CHEMBL4171117

SMILES Oc1c(F)cc(c2cccnc12)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=QIABZCVRDQQJKB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50450447   

TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50450447(CHEMBL4171117)
Affinity DataIC50: >1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50450447(CHEMBL4171117)
Affinity DataIC50:  4nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50450447(CHEMBL4171117)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of c-terminal hexa-His tagged rat S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50450447(CHEMBL4171117)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of c-terminal hexa-His tagged human S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed