BDBM50453140 CHEMBL4213986

SMILES CC(C)Oc1cc(C2CCN(CCOCCOCCNC(=O)CNc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)CC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=XIRQUXILNXIWDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50453140   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453140(CHEMBL4213986)
Affinity DataIC50:  40nMAssay Description:Induction of ALK degradation in human KARPAS299 cells after 16 hrs by immunoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453140(CHEMBL4213986)
Affinity DataIC50:  50nMAssay Description:Induction of ALK degradation in human Kelly cells after 16 hrs by immunoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50453140(CHEMBL4213986)
Affinity DataIC50:  10nMAssay Description:Induction of ALK degradation in human NCI-H3122 cells after 16 hrs by immunoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed