BDBM50453398 CHEMBL2373961

SMILES [H][C@@]12CCC(C([C@@H](C1)c1ccc(Cl)c(Cl)c1)C(=O)OC)N2C

InChI Key InChIKey=AMIHUYQKNJHXPT-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50453398   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50453398(CHEMBL2373961)
Affinity DataIC50: 0.790nMAssay Description:Concentration required to inhibit 50% of radioligand binding ([3H]WIN-35428) to the dopamine (DA) transporter in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50453398(CHEMBL2373961)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50453398(CHEMBL2373961)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50453398(CHEMBL2373961)
Affinity DataIC50: 18nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50453398(CHEMBL2373961)
Affinity DataKi:  0.280nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50453398(CHEMBL2373961)
Affinity DataKi:  11nMAssay Description:Affinity for norepinephrine transporter determined by [3H]nisoxetine displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed