BDBM50462013 CHEBI:8241::Piplartine

SMILES COc1cc(cc(c1OC)OC)/C=C/C(=O)N2CCC=CC2=O

InChI Key InChIKey=VABYUUZNAVQNPG-UHFFFAOYSA-N

Data  4 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462013   

TargetThioredoxin reductase 1, cytoplasmic(Human)
Nantong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462013BDBM50462013(CHEBI:8241 | Piplartine)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of TrxR in human BEL-7402/5-FU cells by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Nantong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462013BDBM50462013(CHEBI:8241 | Piplartine)
Affinity DataIC50: 4.59E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed