BDBM50468475 CHEMBL4279887::US10968163, Compound 3j

SMILES OC(=O)[C@H]1[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)Oc1ccccc1-c1ccccc1O)c1ccccc1

InChI Key InChIKey=CUZOJEWNJDFTBQ-LJWNLINESA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50468475   

TargetFatty acid-binding protein, brain(Homo sapiens)
The Research Foundation For The State University Of New York

US Patent
LigandPNGBDBM50468475(CHEMBL4279887 | US10968163, Compound 3j)
Affinity DataKi:  180nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein 5(Homo sapiens (Human))
The Research Foundation For The State University Of New York

US Patent
LigandPNGBDBM50468475(CHEMBL4279887 | US10968163, Compound 3j)
Affinity DataKi:  430nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
The Research Foundation For The State University Of New York

US Patent
LigandPNGBDBM50468475(CHEMBL4279887 | US10968163, Compound 3j)
Affinity DataKi:  530nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid-binding protein, brain(Homo sapiens)
The Research Foundation For The State University Of New York

US Patent
LigandPNGBDBM50468475(CHEMBL4279887 | US10968163, Compound 3j)
Affinity DataKi:  540nMAssay Description:Displacement of ANS from recombinant human N-terminal His-tagged FABP7 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
The Research Foundation For The State University Of New York

US Patent
LigandPNGBDBM50468475(CHEMBL4279887 | US10968163, Compound 3j)
Affinity DataKi:  1.59E+3nMAssay Description:Displacement of DAUDA from recombinant human N-terminal His-tagged FABP5 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
The Research Foundation For The State University Of New York

US Patent
LigandPNGBDBM50468475(CHEMBL4279887 | US10968163, Compound 3j)
Affinity DataKi:  3.52E+3nMAssay Description:Displacement of DAUDA from recombinant human N-terminal His-tagged FABP3 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed