BDBM50471873 CHEMBL334488
SMILES COc1ccc(cc1OC1CCCC1)C1(Cc2ccncc2)C(=O)c2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc2C1=O
InChI Key InChIKey=QNGXWECIYPIQPZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50471873
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sw 8 Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Sw 8 Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity at Phosphodiesterase 4 by measuring displacement of (+/-)-[3H]- Rolipram to guinea pig brain membranes.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sw 8 Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Sw 8 Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Concentration to inhibit 50% of Phosphodiesterase 4 (PDE-4) from guinea pig macrophagesMore data for this Ligand-Target Pair