BDBM50479982 Aptivus::CHEBI:63628::Tipranavir::U-140690::US10806794, Compound Tipranavir

SMILES CCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1

InChI Key InChIKey=SUJUHGSWHZTSEU-FYBSXPHGSA-N

Data  1 KI  1 IC50

PDB links: 9 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50479982   

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandPNGBDBM50479982(Aptivus | CHEBI:63628 | Tipranavir | U-140690 | US...)
Affinity DataIC50:  7.20nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair