BDBM50479983 Adefovir Diphosphate

SMILES Nc1ncnc2n(CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O)cnc12

InChI Key InChIKey=MELHEUHXJKQZNC-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50479983   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Afmb-Cnrs-Esil

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479983BDBM50479983(Adefovir Diphosphate)
Affinity DataKd:  7.90E+3nMAssay Description:Binding affinity to HIV1 wild type reverse transcriptase p66/p51 expressed in Escherichia coli assessed as incorporation of drug to DNA by gel electr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Afmb-Cnrs-Esil

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479983BDBM50479983(Adefovir Diphosphate)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of HIV1 wild type reverse transcriptase p66/p51 expressed in Escherichia coli using calf thymus DNA substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed