BDBM50481167 CHEMBL583865

SMILES CCNC(=O)C1N(Cc2ccccc12)C(=O)c1cc(Cl)c(O)cc1O

InChI Key InChIKey=QITRQXXSCAOQLZ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481167   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50481167(CHEMBL583865)Copy SMILESCopy InChI

Affinity DataIC50:  300nMAssay Description:Inhibition of Hsp90 in human H1299 assessed as degradation of Hsp90 client protein AktMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI