BDBM50485839 CHEMBL2170471

SMILES C[C@@H](O)C(=O)N1CCC(CCn2c(Sc3cc4OCOc4cc3Br)nc3c(N)ncnc23)CC1

InChI Key InChIKey=CVBWTNHDKVVFMI-GFCCVEGCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485839   

TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485839(CHEMBL2170471)
Affinity DataIC50:  110nMAssay Description:Inhibition of human HSP90 using BODIPY labelled geldanamycin as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485839(CHEMBL2170471)
Affinity DataIC50:  90nMAssay Description:Inhibition of human HSP90 in HCT116 cells expressing Her2 gene assessed as degradation of Her2 after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed