BDBM50485865 CHEMBL2170485

SMILES Nc1ncnc2n(CCC3CCN(CC3)C=O)c(Sc3cc4OCCOc4cc3Br)nc12

InChI Key InChIKey=GTIZIFKNWFZTKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485865   

TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485865(CHEMBL2170485)
Affinity DataIC50:  60nMAssay Description:Inhibition of human HSP90 using BODIPY labelled geldanamycin as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485865(CHEMBL2170485)
Affinity DataIC50:  49nMAssay Description:Inhibition of human HSP90 in HCT116 cells expressing Her2 gene assessed as degradation of Her2 after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed