BDBM50490738 CHEMBL1863131::DNDI1490391

SMILES CS(=O)(=O)N1CCN(CC1)C(c1cncnc1)c1ccc(cc1F)C(F)(F)F

InChI Key InChIKey=TXJQQKATRADULL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490738   

TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490738(CHEMBL1863131 | DNDI1490391)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed