BDBM50490753 CHEMBL1863455::DNDI1465083

SMILES CC(C)(C)C(=O)N1CCN(CC1)C(c1ccc(cc1)C(F)(F)F)c1cccnc1

InChI Key InChIKey=POOVZUQLHIJQQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490753   

TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Epichem

Curated by ChEMBL
LigandPNGBDBM50490753(CHEMBL1863455 | DNDI1465083)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed