BDBM50491620 CHEMBL2386141

SMILES Fc1ccc(nc1)-c1ccc(cc1)C1(CC1)C(F)(F)F

InChI Key InChIKey=RSFGMSBZSCCKNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491620   

TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491620(CHEMBL2386141)
Affinity DataIC50: >5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed