BDBM50492518 Florbetapir::US10906900, AV45

SMILES CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1

InChI Key InChIKey=YNDIAUKFXKEXSV-NSCUHMNNSA-N

Data  5 KI  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50492518   

TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  2.20nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]BOB-4 from Amyloid beta (1 to 42) (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  30.6nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  76.6nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails US Patent